Spindle Cell Lesions—Neoplastic or Non-Neoplastic?

Spindle Cell Lesions of the Head and Neck – Neoplastic or Non-Neoplastic? Spindle Cell Carcinoma and Other Atypical Spindle Cell Lesions

Spindle cell hemangioma or hemangioendothelioma: A case report

Spindle cell hemangioma is a benign vascular tumor presenting as multifocal red or bluish nodules on the distal limbs. We present a 57-year-old woman with five years history of multiple, soft, violaceous nodules on her hands. Pathologic study indicated spindle cell hemangioma.

Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.

Autotaxin (ATX) is a tumor cell motility-stimulating factor originally isolated from melanoma cell supernatant that has been implicated in regulation of invasive and metastatic properties of cancer cells. Recently, we showed that ATX is identical to lysophospholipase D, which converts lysophosphatidylcholine to a potent bioactive phospholipid mediator, lysophosphatidic acid (LPA), raising the p...

Tubercular Mycobacterial Spindle Cell Pseudotumour: A Case Report

Pseudotumour is a benign inflammatory lesion. Mycobacterial spindle cell pseudotumour (MSP) is a rare pseudotumour. It is a benign proliferation of spindle-shaped histiocytes containing acid-fast mycobacterium, commonly reported in immunocompromised patients. MSP is usually associated with mycobacterium avium complex (MAC). Here, we present the case of a 38-year-old gentleman with acquired immu...

The Spindle Cell Neoplasms of the Oral Cavity

Spindle cell neoplasms are defined as neoplasms that consist of spindle-shaped cells in the histopathology. Spindle cell neoplasms can affect the oral cavity. In the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components. This article aims to review the spindle cell neoplasms of the oral cavity with emphasis on histopathology. ...